The human genome encodes roughly 20, genes, only a few thousand more than fruit flies. The complexity of the human body, therefore, comes from far more than just the sequence of nucleotides that comprise our DNA, it arises from modifications that occur at the level of gene, RNA and protein. In a new study, researchers from the University of Pennsylvania School of Veterinary Medicine show how one of these modifications, which occurs after RNA is translated into proteins, has the power to greatly influence the function of an enzyme called PRPS2, which is required for human life and can become hyperactive in cancer.
This type of protein modification, known as arginylation because it attaches an arginine molecule to the protein, has only recently been characterized, but likely plays an important role in regulating not only PRPS2, but a plethora of other proteins that are necessary for life. Patel of the University of Miami. The research is reported this week in the journal Nature Communications.
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Further studies are needed to elucidate treatments for FI using fiber and dietary modifications. Keywords: Diet; Dietary fiber; Fecal incontinence; Food habits. Abstract Introduction and hypothesis: The objective was to perform a systematic review of the literature to examine original research on the role of diet in fecal incontinence FI with a dual focus on dietary differences in FI and dietary treatments for FI.
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